Get a batch-specific Certificate of Analysis and volume-tiered pricing for 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one — a verified Apixaban synthesis intermediate. Response within 24 Hr.

● Verified CAS Identity   ●  Batch-Specific COA   ●  9+ Countries Served

Apixaban Intermediate (CAS 545445-44-1) — Product Identity

Apixaban Intermediate CAS 545445-44-1 is a key synthesis-stage intermediate in the manufacture of Apixaban, an oral factor Xa inhibitor anticoagulant. This compound sits downstream of the nitrophenyl-dihydropyridinone precursor and is subsequently carried forward through amination and cyclization steps toward the finished Apixaban API. Because it’s a widely referenced intermediate across multiple published Apixaban synthesis routes, its identity is independently confirmed across chemical databases and multiple supplier catalogs — not just a single source’s claim.

Buyers occasionally see this compound listed under alternate names or intermediate-numbering conventions (e.g., “Apixaban Intermediate B” or “Apixaban Inter.”). Regardless of the label used, always confirm the CAS number and molecular formula against the structure provided before ordering.

Why Request a Batch-Specific COA Before Ordering

A generic or templated specification sheet tells you what the compound should look like. A batch-specific Certificate of Analysis tells you what the batch you’re actually receiving looks like. For an intermediate feeding directly into an Apixaban synthesis route, that distinction matters — impurities or assay variation at this stage carry through to the finished API’s impurity profile.

A complete COA for this intermediate should include:

• Assay result with the HPLC method and conditions used
• Individual and total related substances
• Identification confirmation (typically IR or comparison to a reference standard)
• Appearance and, where relevant, water content

If you’re using this intermediate as part of a regulatory filing for an Apixaban API, the batch COA also becomes part of your own supply chain documentation trail — another reason to insist on batch-specific data rather than a static, reused specification sheet.

Bulk Pricing and Order Details

Pricing is volume-tiered — larger orders receive lower per-kilogram pricing. Submit your target volume through the request form below for an order-specific quote.

A small sample is available before bulk commitment, so you can independently verify assay and related substances against your internal specification before placing a full order.

Documentation Provided With Every Order

Certificate of Analysis
Batch-specific COA with assay, related substances, and identification results.

MSDS/SDS
Current safety data sheet covering handling, storage, and hazard classification.

Structure Confirmation Data
NMR and mass spectrometry data available on request, particularly for first orders or reference-standard use.

Certificate of Origin
Export documentation required for customs clearance and import registration.

Manufacturing and Quality Assurance

This intermediate is manufactured under a documented quality system, with in-house testing performed on every batch before release. Given this compound’s role as a direct precursor in an anticoagulant API synthesis, batch-to-batch consistency in assay and impurity profile is treated as a release-critical specification, not a secondary check.

Manufacturing capacity supports both trial-scale and repeat bulk orders — confirm your projected annual volume when requesting a quote so we can advise on appropriate scale-up lead time.

Export Markets and Shipping Capability

We export this intermediate, supporting both regulated and semi-regulated market buyers. Shipments are available by air or sea freight depending on order volume and timeline.

For buyers whose Apixaban filing requires documented traceability of this intermediate’s supply chain, we can provide the supporting documentation typically requested during regulatory review — confirm your specific requirement when requesting a quote.

Why Source This Intermediate From Us

• Verified chemical identity —Apixaban Intermediate CAS 545445-44-1 confirmed against independent chemical databases, not just internal catalog listings
• 9+ of experience supplying Apixaban and related anticoagulant synthesis intermediates
• Batch-specific COA issued with every shipment, with structure confirmation data available on request
• Responsive technical support for documentation queries, before and after order confirmation

How to Request COA and Pricing

1. Submit Your Requirement — Fill out the form with your target volume, intended use, and timeline.
2. Receive COA Sample, Spec Sheet & Pricing — We’ll respond with a current specification sheet, sample COA, and volume-tiered indicative pricing.
3. Request a Sample (Optional) — Independently test a small sample against your specification before committing to bulk volume.
4. Confirm Order & Documentation — Finalize order terms, payment schedule, and export documentation for shipment.

Request COA & Pricing for CAS 545445-44-1

Frequently Asked Questions

Verified CAS identity. Batch-specific documentation. Volume-tiered pricing.
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